Infectious disease remains one of medicine’s greatest challenges. Indeed, globalization has rendered the problem more press-ing than ever before: viruses and bacteria once relegated to faraway locales can reach the other side of the planet in a day’s time—and propagate unchecked in their new environs. In this exclusive online issue, leading researchers describe their efforts to tame some of the most intractable diseases of our time. Stanley Prusiner explains how new tests are enabling fast detection of prions, the agents that cause mad cow disease. John Young and his colleagues discuss strategies for the prevention and treatment of anthrax. And David Ojcius and his collabo-rators report on the latest approaches to stemming the spread of chlamydia.
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